English translation for "clonal expansion"
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- 克隆扩充
克隆扩增
Related Translations:
- Example Sentences:
| 1. | Differentiating 3t3 - l1 preadipocytes undergo clonal expansion induced by acylation stimulating protein
前脂肪细胞分化为成熟脂肪细胞后的再增殖 | | 2. | Thus , it is evident that 3t3 - l1 preadipocytes could differentiate into adipocytes without dna synthesis and mitotic clonal expansion
这些结果说明克隆扩增和dna复制并不是3t3 l1前脂肪细胞分化的必需步骤。 | | 3. | By inducing 3t3 - l1 preadipocyte with individual hormone , it was identified that the mitotic clonal expansion was induced only by insulin , not by 1 - isobutyl - 3 - methylxanthine or dexamethasone
有报道用药物抑制了克隆扩增的同时抑制了细胞的分化。我们发现克隆扩增是仅由胰岛素诱导引起的。 | | 4. | However , significant fraction of 3t3 - l1 preadipocytes differentiated into adipocytes without the mitotic clonal expansion when the preadipocytes were induced with the combination of 1 - isobutyl - 3 - methylxanthine and dexamethasone
用地塞米松和ibmx对细胞进行诱导不发生克隆扩增，而细胞也能部分分化，分化形成的脂肪细胞未经过dna复制。 | | 5. | Furthermore , when normally induced 3t3 - l1 preadipocytes were treated with pd98059 ( an inhibitor of mek - 1 ) , to block the activation of erk1 and 2 , the mitotic clonal expansion was blocked , while adipocyte differentiation was not affected
我们用有丝分裂原激活蛋白激酶激酶（ mapkk / mek1 ）的抑制剂pd98059与诱导分化激素及药物一起对细胞诱导分化，克隆扩增不发生，但细胞分化未受影响。 | | 6. | Upon the differentiation induction of 3t3 - l1 preadipocytes by hormone cocktail containing 1 - isobutyl - 3 - methylxanthine , dexamethasone and insulin , the preadipocytes undergo ~ 2 rounds of mitotic clonal expansion , which just precedes the adipogenic gene expression program and has been thought to be an essential early step for differentiation initiation
诱导分化的早期细胞会进行约两轮的细胞分裂，被称为克隆扩增。克隆扩增以前一直被认为可能有利于染色体的重构以易化分化所需要的基因表达，因此克隆扩增可能是3t3 l1前脂肪细胞分化所必需的过程。 | | 7. | Disruption of lipid rafts and caveolae by depleting cellular cholesterol with cholesterol - binding reagent , - methylcyclodextrin or filipin , blocks the igf - 1 receptor signaling in 3t3 - l1 preadipocyte . both hormone induced adipocyte differentiation and mitotic clonal expansion are inhibited by lipid rafts and caveolae disruption . however , a nonspecific lipid binding reagent , xylazine , does not affect adipocyte differentiation or mitotic expansing
利用胆固醇结合试剂，如甲基环糊精和菲律宾菌素，减少细胞胆固醇的含量，破坏细胞膜上脂质筏/质膜微囊的结构，抑制了igf - 1受体信号诱导的3t3 - l1前脂肪细胞的分化以及克隆扩增。 |
- Similar Words：
- "clonal deletion" English translation, "clonal deletion theory" English translation, "clonal deterioration" English translation, "clonal difference" English translation, "clonal diversity" English translation, "clonal formation unit" English translation, "clonal growth" English translation, "clonal ignorance" English translation, "clonal inhibitory factor" English translation, "clonal latex" English translation
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