The mechanism of chloramphenicol toxicity is apparently failure of the newborn to conjugate chloramphenicol with glucuronic acid due to inadequate activity of hepatic glucuronyl transferase 氯霉素中毒的机制显然是由于新生儿肝脏的葡萄糖醛酸转移酶活性不足，不能使氯霉素与葡萄糖醛酸结合。
2.
Hyaluronic acid ( ha ) is a high molecular weight linear polysaccharide composed of repeating disaccharide units of d - glucuronic acid ( glclia ) and n - acetyl - d - glucosamine ( glcnac ) linked by 3 - 1 - 3 and p - 1 - 4 glycoside bonds 透明质酸( hyaluronicacid )是一种由葡萄糖醛酸( glcua )和n -乙酰氨基葡萄糖( clcnac )以- 1 - 3和- 1 - 4糖苷键相连的二糖单位重复构建而成的，具有生物相容性的高分子聚合物。
3.
Udp - glucuronosyltransferases ( ugts ) are glycoproteins localized in the endoplasmic reticulum that catalyze the conjugation of a broad variety of endogenous and exogenous lipophilic aglycon substrates ( such as bilirubin , steroid hormone and drugs , insecticide , etc ) with glucuronic acid using udp - glucuronic acid ( udpga ) as the sugar donor . ugts are a gene superfamily of phase ii drug - metabolizing enzymes , they are responsible for the glucuronidation of a significant number of different functional groups ( e . g Ugts能催化各种各样外源和内源的亲脂性糖苷配基底物与葡醛酸的结合，该反应是机体清除外源性(如药物和杀虫剂)和内源性(如胆红素和甾体激素)亲脂性化合物的一个主要方式，也是药物相代谢的重要方式。
4.
[ objective ] heparin is linear polysaccharides consisting of repeating disaccharide unit backbones of n - acetyl - d - glucosamine that is linked to d - glucuronic acid . the disaccharide repeat unit can be modified to include n - and o - sulfation ( 6 - o and 3 - o sulfation of the glucosamine and 2 - o sulfation of the uronic acid ) . these specific sulfate patterns are involved in the interaction of heparin with other molecules [目的]肝素是由n -乙酰葡萄糖胺与d -葡萄糖醛酸以1 4糖苷键连接起来的重复二糖单位组成的线性多糖，葡萄糖胺可带有n -硫酸基团，可在c6上形成0 -硫酸酯，带有硫酸基团的独特结构参与了肝素与其他分子的相互作用。
