Humans have not found good therapy to influenza and still depend on vaccines . but the variation of influenza virus reduces the efficacy of the inactivated vaccines that is licensed for parenteral administration in humans . so it is urgent to find a novel influenza vaccine that is cross - protective to different subtypes 目前对于流感尚无有效的治疗手段,仍以疫苗接种为主,但由于流感病毒的抗原变异性强,当前使用的三联灭活疫苗效果并不理想,迫切需要研制具有交叉保护作用的新型疫苗。