Owing to the common expression of egf in various organs of mouse , it could be deduced that the role of egf was mainly autocrine and paracrine actions , and its endocrine role was also not excluded owing to its high expression abundance in submaxillary gland 由于egf在小鼠各器官中表达的普遍性,可以推测egf的作用以旁分泌和自分泌作用为主,但它在颌下博士学位论文“ tnegfalelittin ”嵌合基因构建及有关基因重组表达的研究等器官中的高表达表明其也具有内分泌作用。