The clsp gene is located approximately 3 kb and 90 kb centromeric to the clr and cls gene , respectively , and their genes form a short cluster in a region of about 115kb in 12pl3 . the cluster gene arrangement and the sequence similarities of the cub and trypsin - like serine protease domain of clsp with other complement component 1 subcomponents supported a common evolutionary history by consecutive gene dup 同样利用pcr检测了clspmrna在人正常组织中的分布，结果发现，人clspmrna广泛表达于人正常组织中，如在胎盘、肝脏、肾脏、胰腺中表达量较高，在肺、脾、前列腺、卵巢、结肠、外周血组织有中度表达，而在心脏、骨骼肌、胸腺、翠
2.
Because of its fully sequenced genome and the most complete , contiguous nucleotide sequence of centromeric dna in plants , arabidopsis was chose as the base to construct plant artificial chromosome . we identified two candidate yac clones , cic8h8 and cic6f6 , which are both proved to have the 178 bp arabidopsis centromeric repeat sequences 我们通过pcr和序列分析，选择了含有拟南芥着丝粒区178bp串连重复序列的yac克隆作为构建人工染色体的基础，同时也克隆了拟南芥的端粒和ars等序列。
