Chemonucleolysis is contraindicated in patients who are allergic to papaya or who have previously been injected with chymopapain 对番木瓜过敏的病人，或以前曾经注射过木瓜凝乳蛋白酶的人，化学核溶解法是禁忌证。
2.
Following the chymopapain injection ， the patient may experience increased back pain for several days to several weeks but may have immediate relief of leg pain 注射木瓜凝乳蛋白酶后，病人可体验到腰部有几天或几周的加重，但小腿疼痛却很快消失。
