Diagnosis for endemic cretinism and endemic subclinical cretinism 地方性克汀病和地方性亚临床克汀病诊断
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Cretinism doesn ? t sink any lower 没有比白痴更蠢的了。
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Cretinism doesn t sink any lower 再痴呆也不过如此吧。
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Patients with cretinism , a syndrome caused by lack of sufficient th during foefetal and neonatal periods , suffer mental retardation , antaxia , spasticity and deafness , indicating severe brain anatomical and functional defects 文献显示，这一过程的失调可能就是甲低时智能障碍、学习和行为缺陷的主要原因。
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( 6 ) pdgf may initiate neuronal differentiation in nsc . nsc induced by pdgf , transcription and translation level of different thrs genes were up - regulated compared with the nsc induced by serum . the results made a great foundation for the further research of the important role of thrs during the cns development , and have much clinical significance on therapy of cretinism ^ subcretinism a Thr各亚型在不同分化细胞中表达不一致： （ 0l ；能诱导nsc向少突胶质细胞分化，并通过thr各亚型的时空表达来发挥其重要生理作用门印叩朴能引发vc向神经几分化，与10血清诱导分化相比能在转录与翻译水平上提高nsc分化后thr各亚型的表达本研究结果将为深入研究t在脑发育中的作用提供宝贵的实验依据，并对克汀病、亚克汀病以及ms脱髓鞘病等的临床治疗提供新途径，具有重要指导意义。
