| 1. | Histomorphometry showed marked enhancement in nerve regeneration through allografts injected with schwann cells
组织形态测定法显示，注射过雪旺细胞的同种异体移植物对神经再生有显著的促进作用。 |
| 2. | In this study , with adeasy vector system , the recombinant adenovirus containing huctla4 - ig gene was constructed
目前，关于基因转移huctla4 - ig诱导同种异体移植物耐受的研究，国外仅有少数实验室开展，国内未见报道。 |
| 3. | Prolonged cold - preservation of nerve allograft tissue could serve as a means to produce unlimited graft material for use in peripheral nerve reconstruction
在周围神经重建领域，神经的同种异体移植物经延长时间的冷冻保存法处理可制作移植物材料，应用前景乐观。 |
| 4. | Histomorphometry distal to the graft showed robust regeneration in the isograft and 7 - week cold - preserved groups when compared to the untreated allograft group
自体移植组和冷冻保存7周移植组与未处理同种异体移植物组相比，在移植物远端可发现旺盛的神经再生状况。 |
| 5. | There was a shift from an interferon - gamma - producing cellular response ( untreated allografts ) to an absence of response ( 7 - week cold - preserved allografts and isografts )
从未经处理的同种异体移植物一直到冷冻7周的同种移植物和自体移植物， gamma干扰素导致的细胞免疫反应逐渐减弱，最后消失。 |
| 6. | The goal of this study was to determine the effect of varying durations of cold - preservation on the immunogenicity of nerve allografts and their subsequent ability to facilitate neuroregeneration across a short nerve gap
本次实验的目的在于检测不同的冷冻保存时间对于神经同种异体移植物免疫原性的影响，同时测定其对短段神经缺损再生的作用。 |
| 7. | We postulate that pretreatment with fty reduce the t cell population by apoptotic death , in the midest of death , the apoptotic cell actively inhibit the maturation of dc . in addition to these , fty also down - regulate the cd25 on the t cell membrane
基于我们对fty作用机制的认识，我们首次提出术前使用fty并于围手术期维持用药的方案，并用这一方案成功诱导了小鼠对同种异体移植物的稳定耐受。 |
| 8. | In terms of regulatory t cell , cd4 + cd25 + t cell is representitive . ln naive individuals , cd4 + cd25 + t cells function as self tolerance , in recipients with long term survival allograft . they play an important role in suppression of allograft rejection . immune regulation potent cd4 + cd25 + t cells can be recovered from recipients with long term survival allografts . such regulatory t cells can suppress t cell mediated rejection in vitro and in vivo
其中， cd4 + cd25 + t细胞是具有代表性的调节性t细胞。在未经处理的机体内， cd4 + cd25 + t细胞对保持自身耐受起着关键的作用。在同种异体移植物长期存活的受体内， cd4 + cd25 + t细胞对抑制同种异体移植物排斥反应也起到很重要的作用。 |
