English translation for "抗原提呈"
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- angtigen presentation
Related Translations:
呈: Ⅰ动词1.(呈现) assume (form, colour, etc.) 短语和例子呈出笑容 show a smiling face; 龙凤呈祥 prosperity brought by the dragon and the phoenix; 大海呈天青石色。 the sea was of a lapis lazuli blue. 叶呈椭圆形。 the leaf is 惊呈: vomiting due to fright 签呈: [旧时用语] brief document submitted to a superior; petition
- Example Sentences:
| 1. | Major histocompatibility complex ( mhc ) class ii molecules are the predominant presenters of exogenous antigens to t helper cells
主要组织相容性复合体( mhc )类分子可将外源性抗原提呈给t辅助细胞。 | | 2. | Constitutive expression of class ii mhc is restricted to " professional " antigen - presenting cells but can be induced on various tissues by gamma interferon
Mhc -类的组成型表达仅限于“专职性”抗原提呈细胞，但细胞因子如ifn -可引起诱导型类分子表达。 | | 3. | Cells of the immune system taking part in tumor - host interaction include t cells , natural killer cells ( nk cells ) and antigen - presenting cells ( apc , such as dendritic cells , b cells , macrophages )
参与肿瘤免疫的免疫细胞主要有t细胞， nk细胞和抗原提呈细胞( apc ) 。 | | 4. | But the systedric bounosuppressive agents , which are obviously a double - bladed sword , have a lot of side effects and toxicities , which have formed hapetus to seek methods and strategies for induction of donor - specilic tolerance
树突状细胞( dendritic cells , dc )作为一类具有最强抗原提呈功能的细胞群体，在识别和提呈抗原启动免疫应答、诱导移植排斥中起重要的作用。 | | 5. | Dendritic cells ( dc ) are the most potent professional antigen - presenting cells ( apc ) , required for the initiation of immune response . for all that the mechanism of dc functions are not fully elucidated
树突状细胞( dendriticcell ， dc )是一种重要的专职抗原提呈细胞( apc ) ，具有刺激初始型t细胞增殖、启动初次免疫应答的独特功能，是t细胞免疫应答的直接启动者和调控者。 | | 6. | As c ii ta is a single gene or protein that affects a large family of genes , it represents an ideal target for intervention in the class ii antigen presentation pathway , for immune suppression in transplantation and autoimmumty
作为影响一个大基因家族的单个基因或蛋白质， c ta是对mhc -类的抗原提呈过程进行干预的理想靶点，可以在自身免疫损伤和移植排异过程中进行免疫抑制干预。 | | 7. | It delivers the false ? folding peptides for presentation to proteasomes in normal cells , while in tumor cells it acts as main tumor - resistant antigen , inducing specific immune response . recent research found that grp94 also relates with cell cycles , differentiation and apoptosis
此外发现它还具有抗原提呈作用，在正常细胞中参与折叠错误蛋白到蛋白酶体的提呈；在肿瘤细胞中作为主要的肿瘤排斥抗原，引发针对该肿瘤细胞的特异性免疫反应。 | | 8. | Unfortunately , tumor cells can secrete immunosuppressor factors ( such as il - 10 , tgf - p , vegf ) to interfere with dc maturation and function . to overcome tumor - mediated inhibition of dc maturation and function in vivo , immunopotentiating cytokines ( such as il - 7 , il - 12 ) were used for gene - modification of dc , which has proven to be an efficient way to treat cancer in animal models
虽然有直接瘤内注射dc诱导抗肿瘤免疫效应的报道，但肿瘤局部往往是一个处于高度免疫抑制状态的微环境，肿瘤细胞分泌的可溶性介质（如ill 、 tgf卜vegf等）能抑制dc的分化成熟，下调dc表面共刺激分子的表达和iliz的分泌，从而抑制dc的抗原提呈功能，亦对t细胞功能有显著的抑制作用。 | | 9. | Dendritic cells ( dc ) is the most powerful apc , which can markedly increase the antigen - presentation capacity by maximizing the pepitide - mhc complexes on the cell surface and upregulating the co - stimulatory ligands b7 - 1 and b7 - 2 , adhesion moleculees such as il - 12 that promote full activation of lymphocytes . full activation of antigen - specific t cells requires two signals - one signal coming via the tcr and the other signal through engagment of co - stimulatary molecules . t cells receiving one signal via their tcr are turned off by mhc ( major histocompatibility complex ) , via t cell cd28 binding to b7 on the dc induce tlymphokine and t cell proliferatiion
T细胞介导的细胞免疫在控制肿瘤生长方面发挥着重要作用， t细胞在发挥抗瘤效应(分泌细胞因子和直接杀伤)之前必须先经过活化，体内专职抗原提呈细胞( apc )细胞并使其活化，树突状细胞( dendriticcell , dc )为t细胞的激活提供双重信号， t细胞借助tcr识别由dcmhc分子递交的抗原肽后，通过tcr - cd3复合体传递抗原特异性识别信号(第一信号) ，以cd28为主的t细胞表面辅佐分子识别dc表面b7分子，传递非特异性协同刺激信号(第二信号) ，在机体抗肿瘤免疫应答中处于核心地位。 | | 10. | Dendritic cells are characterized by their ability to efficiently present antigen , and are uniquely equipped to stimulate naive t cell responses . immature dendritic cells acquire antigens from throughout the peripheral body , then migrate to t - lymphocyte - dependent areas of lymph nodes . thus , dendritic cells act as bridges , operating at the interface of innate and acquired immunity
作为机体免疫系统中功能最强的专职性抗原提呈细胞( antigen - presentingcells , apc ) ，树突状细胞( dendriticcells , dc )能高效地摄取、加工处理和提呈抗原，具有较强的迁移能力，并能显著地激活初始型t细胞以启动t细胞免疫应答反应，此外， dc与b细胞以及nk细胞等也存在着相互作用，可见， dc在连接天然免疫和获得性免疫之间起着非常重要的作用。 |
- Similar Words：
- "抗原特异性的巨噬细胞抑制因子" English translation, "抗原特异性辅助细胞因子" English translation, "抗原特异性辅助因子" English translation, "抗原特异性巨噬细胞抑制因子" English translation, "抗原特异性细胞的细胞毒性" English translation, "抗原提呈细胞" English translation, "抗原提呈细胞,呈递抗原细胞" English translation, "抗原提呈运转体" English translation, "抗原提示细胞" English translation, "抗原同质性" English translation
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