The high parathormone levels increase osteoclast activity and produce irregular bone resorbtion with microfractures and hemorrhage and macrophage proliferation and fibrous connective tissue proliferation 高甲状旁腺激素水平提高了破骨细胞的活性并导致不规则的骨溶解吸收,伴随微骨折、出血、巨噬细胞增殖及纤维性结缔组织增生。