| 1. | Agmatine inhibits the afferent activity of carotid baroreceptor in rats
胍丁胺抑制大鼠颈动脉窦压力感受器活动 |
| 2. | Differential responses of regional vascular beds to local injection of agmatine in rats
区域性血管床对局部注射胍丁胺的不同反应 |
| 3. | Action of agmatine on tension of isolated aortic artery and its receptor mechanism in rats
胍丁胺对离体大鼠主动脉张力的影响及其受体机制 |
| 4. | However , little is known about cellular mechanism underlying the cardiovascular actions of agmatine
然而，有关胍丁胺心血管作用的细胞机制，至今尚未见报道。 |
| 5. | It has been known that agmatine was widely distributed in cardiovascular system of mammalian tissues , suggesting that agmatine could act on cardiovascular system
已知心血管系统能合成和贮存胍丁胺，从而提示其可能对心血管系统有作用。 |
| 6. | And agmatine also decreased apa , vmax ) v dd , rpf and apd50 , 9o in a concentration - dependent manner in human atrial fibers and guinea pig papillary muscles
胍丁胺还可浓度依赖地缩短离体豚鼠乳头肌与人心房纤维的动作电位的时程，抑制v _ ( max )和降低vdd和rpf 。 |
| 7. | In 1994 , li et al isolated agmatine from cow brain . like clonidine , agmatine is an endogenous agonist at imidazoline receptors ( ir ) and a noncatecholamine ligand at ( ai - adrenergic receptors ( ( x2 - ar )
胍丁胺( agmatine )是1994年li等从牛脑中分离纯化的一种内源性可乐定置换物质( clonidinedisplacingsubstance ， cds ) ，它可能作为一种新型的神经递质或调质。 |
| 8. | 1 . hemodynamic effects of agmatine in dahl salt - sensitive hypertensive and dahl salt - resistant rats the hemodynamic effects of agmatine were investigated in anaesthetized dahl salt - sensitive ( ds ) hypertensive and dahl salt - resistant ( dr ) rats . the results are as follows : ( 1 ) agmatine ( 1 , 10 , 20 mg / kg , iv . )
一、胍丁胺对dahl盐敏感型高血压大鼠和dahl盐抵抗型大鼠血流动力学的影响在麻醉dahl盐敏感型( ds )高血压大鼠和dahl盐抵抗型( dr )正常血压大鼠，研究了静注胍丁胺对血流动力学的影响。 |
| 9. | The purposes of the present study were to investigate ( 1 ) the hemodynamic effects of agmatine in anaesthetized dahl salt - sensitive ( ds ) hypertensive and dahl salt - resistant ( dr ) rats ; ( 2 ) the effect of agmatine on vascular tension in the isolated aortic artery of rats and the underlying receptor mechanism ; ( 3 ) the effects of local injection of agmatine on femoral , renal , and mesenteric vascular beds by constant flow perfusion method ; ( 4 ) the effect of agmatine on l - type calcium current ( / ca - t ) in rat ventricular myocytes with whole - cell configuration of the patch - clamp technique ; ( 5 ) the effects of agmatine on free intracellular calcium concentration ( ca2 + d of isolated rat ventricular myocytes
( 3 )采用后肢、肾脏和肠系膜动脉在体恒流灌注法，观察向灌流环路中直接注射胍丁胺的血管效应。 ( 4 )应用全细胞膜片箝技术，观察胍丁胺对大鼠心室肌细胞l -型钙通道电流( i _ ( ca - l ) )的影响。 ( 5 )用fluo3 - am负载分离的大鼠心室肌细胞后，由激光共聚焦法测定单个心室肌细胞[ ca ~ ( 2 + ) ] _ i的荧光强度，观察胍丁胺对分离大鼠心室肌细胞内游离钙浓度( [ ca ~ ( 2 + ) ] _ i )的影响。 |
