| 1. | Autoantibodies can also recognize self - antigens already in tissues and generate immune complexes on - site
自体抗体也能辨识组织中的自体抗原，在该组织中形成免疫复合体。 |
| 2. | Systemic lupus erythematosus ( sle ) and autoimmune thyroid diseases are both marked by pathogenic autoantibodies
摘要病理性自体抗体在全身性红斑狼疮及自体免疫性甲状腺疾病都扮演重要角色。 |
| 3. | One thing about lupus has long been clear : the autoantibodies that are its hallmark contribute to tissue damage in more than one way
关于狼疮，科学家长久以来就清楚一项事实：狼疮的特徵是自体抗体，而这些抗体可经由许多方式造成组织损伤。 |
| 4. | Neonatal lupus erythematosus ( nle ) , an immune - mediated disease with multisystem involvement in infants , is associated with the transplacental transfer of maternal autoantibodies
摘要新生儿红斑性狼疮是一种由母亲的自体抗体藉由胎盘传给胎儿的免疫性疾病。 |
| 5. | However , recent data suggest muscarinic acetylcholine receptor machr autoantibody plays an important role in the disease pathogenesis . we have demonstrated different machr autoantibodies in different ss patients
最近研究显示蕈毒乙醯胆硷受体之自体抗体，在修格连症候群致病机转中，扮演重要角色。 |
| 6. | But other work indicates that , in addition , the b lymphocytes of lupus patients are inherently deranged ; they are predisposed to generate autoantibodies even when the self - molecules they encounter are perfectly normal
但原因不只如此，其他研究显示，狼疮患者的b淋巴球生来就表现异常；即使它们遇到的是完全正常的自体分子，也会倾向生产自体抗体。 |
| 7. | One region , for example , apparently harbors genes that participate in producing autoantibodies that recognize components of the cell nucleus ( although the region itself does not encode antibodies ) ; another influences the severity of the kidney inflammation triggered by lupus - related immune complexes
举例来说，有一段区域显然与细胞核自体抗体的制造有关，不过那个区域并没有抗体基因；另一段区域，则会影响免疫复合体所引发肾脏炎的严重程度。 |
| 8. | Mixed connective tissue disease ( mctd ) was defined as a connective tissue disorder characterized by the presence of high titers of a distinct autoantibody in combination with clinical features commonly seen in systemic lupus erythematosus ( sle ) , scleroderma , and polymyositis ( referred to as overlap syndrome )
摘要混合性结缔组织疾病是一种结缔组织异常的疾病，合并有高价且明确的自体抗体，临床上常有类似全身性红斑性狼疮，硬皮症及多发性肌炎的表现。 |
