| 1. | Study of the accuracy of prediction algorithms in biology
基于信息熵的蛋白质二级结构预测算法的准确性研究 |
| 2. | Another research subject is the prediction of protein secondary structure
论文的另一个研究主题是蛋白质二级结构的预测方法。 |
| 3. | A novel approach was introduced to process and analyze the data sets for protein secondary structure prediction based on database technologies via constructing a database of the prediction data sets
摘要将数据库技术应用到蛋白质二级结构预测的样本集处理和分析上，建立了二级结构预测样本集数据库。 |
| 4. | By the use of cirular dichroism and fluorescence techonologies to predict the secondary structure of protein , to determine the secondary structure of a protein , and to explore the unfold - refold mechanism of a protein
运用圆二色谱和荧光技术分析预测蛋白质二级结构，研究蛋白质的稳定性与蛋白质的变性复性动力学机制。 |
| 5. | This thesis discussed two important topics in the biological sequence analysis . safss and data mining method for protein secondary structure prediction are of importance , which lay the foundation for the further research for author
本文的研究内容是生物序列分析中两个重要课题,研究中提出的safss比对方法和基于序列模式挖掘的蛋白质二级结构预测方法具有一定的研究意义,为作者进一步进行序列分析研究奠定了基础。 |
| 6. | The biological sequence analysis research content mainly includes the sequence alignment , the protein structure prediction , and the genome sequence analysis etc . the thesis studied the pair - wise sequence alignment algorithms and the protein secondary structure prediction methods emphatically
生物序列分析的主要研究内容包括序列比对、蛋白质结构预测、基因组序列分析等。本论文着重研究了双序列比对算法和蛋白质二级结构的预测方法。 |
| 7. | The extracellular 100pl ( ecl1 ) and ecl2 was linked by disulfide bond to maintenanced the stability of the protein secondary structure . in recent years , we showed that ccr5 as a co - receptor could interact with hiv - 1 infect ion . ccr5 was paid closed attention to since it was cloned in 1996 . the aim is to - obtain the sequence of first extracillular domain of 3 chemokine receptor 5 ( ccr5 ) n - terminal gene fragment with high level expression in e . coli and to prepare its specific antibody f ( ab ' ) ; , and its detected method
Ccr5具有g蛋白偶联受体家族( g - proteincoupledreceptors ， gpcrs )所特有的7个跨膜区( transmembrinedomains ， tm ) ，呈螺旋， tm的氨基酸有很高的保守性，膜外第一襻( extracellularloop1 ， ecl1 )和ecl2之间有二硫键相连，以维持蛋白质二级结构的稳定性。 |
| 8. | 4 . alignment was made between 8 second - structure of proteins referring to the difference of 8 cdna sequences and corresponding amino acid sequences of them and the phylogenetic tree drawn among them and five pieces of conclusions obtained are as follows : there exists great difference in the four structures as " a turn and coil " of the second structure of proteins between boacal5 " and boccal5 " ; difference also exists in the alignment of the four structures as above between boacal5 " and boccal5 ' ; ( 3 ) only the structure of " turn " changes in the comparison of bogcal5 " with boacal5 " the same level of comparison as above ; one amino acid differs between the protein sequence of boccal5 " and bocal5 ' , and accordingly , " " structure exhibits difference between the above two ; both the amino acid sequence and the second - structure of proteins of bogcal5 " and bcpcal5 "
4 、结合8种cdna序列、相应氨基酸序列之间的差异及它们之间的同源性进化树，对8种蛋白质二级结构进行了比较，得到以下5点结论： boccal5 ’和boacal5 ’的蛋白质二级结构在“ 、 、 turn和coil ”四种结构上均存在较大差异； boccal5 ’和bogcal5 ’之间在蛋白质二级结构水平上在上述四种结构中也都存在不同之处；在蛋白质二级结构上， bogcal5 ’和boacal5 ’之间只有“ turn ”结构发生了变化； boccal5 ’和bocal5 ’之间的差异只有一个氨基酸，而在蛋白质二级结构上折叠结构则不相同： bogcals ’与bcpcals之间氨基酸序列和蛋白质二级结构完全相同。 |
