The series of trials indicated some ions were helpful to stabilize the configuration of cml and the inhibition of cml ' s activity by edta was dual . edta inhibited the agglutinate activity of cml directly and also made cml lose its agglutinate activity through chelating the ions in cml 以上结果表明edta对cml活性的抑制是双重的:即edta可以通过非螯合金属离子的方式抑制cml的活性,也可以通过螯合cml分子中的金属离子使其失去活性。