| 1. | The small molecule causing the conformational change is an allosteric effector .
引起结构变化的小分子叫做变构效应场。 |
| 2. | Proteins which have two separate but interacting sites are called allosteric proteins .
这种具有两个不同而又相互作用位置的蛋白质叫做变构蛋白质。 |
| 3. | Allosteric enzymes may have more than one modulator
它可以有一个或多个调节物。 |
| 4. | Allosteric enzymes possess an allosteric site in addition to their active site
别构酶控制着别构部位和它的活性部位。 |
| 5. | Allosteric site a part of an enzyme to which a specific effector or modulator can be attached
别构部位：可以结合特定效应物或者调节物的酶的一个部分。 |
| 6. | Obviously the involvement of " allosteric effects " in the action of growth regulators is highly specific and equally speculative
在生长调节剂的作用中涉及“变构效应， ”这显然是高度特殊又是高度推测性的。 |
| 7. | When the product accumulates beyond an optimal amount it binds to a site ( allosteric site ) on the enzyme , changing the shape so that it can no longer react with its substrate
当产物积累超出最佳数量时，它将与酶的一个氨酰基位点（变构位点）结合改变其形状，使其不能长时间与底物发生作用。 |
| 8. | Allosteric enzyme an enzyme whose catalytic activity can be modified by the noncovalent binding of a particular metabolite ( a modulator ) at a site ( the allosteric site ) other than the active site
别（变）构酶：这种酶除了有活性中心外，还有一个别构中心，当专一性的代谢物非共价的结合到别构中心上时，它的催化活性即发生改变。 |
| 9. | In escherichia coli , arog gene encodes phenylalanine - sensitive 3 - deoxy - d - arabino - heptulosonate - 7 - phosphate synthase isoenzyme arog that catalyzes the first committed step of shikimate pathway . here we study the essential amino acid residues involved in the formation of feedback inhibition site of arog , and the effects of n - terminus on feedback inhibition and its quaternary structure , and the importance of the structural " d2 " symmetry to allosteric inhibition
本博士论文工作以大肠杆菌k - 12来源的arog为研究对象，通过定点突变、反馈抑制实验和酶学动力学参数的测定，深入地研究了arog的反馈抑制位点的特性，并对arog的n -末端在反馈抑制机理和维持稳定四级结构中的作用，以及蛋白质结构的“ d2 ”对称性对酶功能的重要性等进行了具体的研究。 |
