| 1. | The above results verified the good cytocompatibility of the amphiphile - amino acid hybrid modified pdl - la scaffold 利用该技术,测得生物大分子表面截留层的厚度为10上0pm 。 |
| 2. | Up to now , almost no papers concerning with urease / amphiphile mixed lb films and pure urease lb films have been reported 目前几乎没有关于脲酶两亲性化合物混合lb膜、纯脲酶lb膜的文献报道。 |
| 3. | Combining the surface self - segregation behavior of amphiphile and salt - leaching technique , the ecm - like surface , with peo spacer combining amino acid ( rgd ) , was successfully constructed in - situ on pdl - la 3d tissue engineering scaffold 本论文的实验结果在peo链长为2000分子量时对软骨细胞的粘附与生长有最佳的作用。 |
| 4. | Experimental conditions for the formation of urease / amphiphile mixed langmuir films at the air / water interface and the transfer of the langmuir films onto the surface of different substrates have been explored 研究并得到了亚相中的脲酶在空气水界面与两亲性化合物形成混合langmuir膜及将langmuir膜转移到各种基片表面的实验条件。 |
| 5. | Based on the " self - migrating and surface - segregation " behavior , the amphiphile segregation surface was therefore constructed on hydrophobic pdl - la matrix , which containing the structure of peo spacer combining cell adhesion ligands to mimic the extracellular matrix ( ecm ) 基于两亲共聚物在疏水高聚物材料内的自迁移和表面富集行为,在聚乳酸材料上构建了以peo桥联氨基酸或整合素配体多肽片段的类细胞外基质表面。 |
| 6. | The main works are shown as the below : ( 1 ) . langmuir monolayer of behenic acid and dppc surfactants behenic acid is a classical amphiphile , it has been applied to prepare functional lb films and quantum semiconducting particle films . therefore , it is of essential importance to study behenic acid monolayer at the air / aqueous interface ; at additional , in the different subphase ( h2o cdcl2 ) conditions behaviors of behenic acid monolayers have been studied ; moreover , we study dppc monolayer at the aqueous subphase , stability of dppc at the different surface pressures and speed rates 研究内容如下: ( 1 )二十二酸、 dppc单分子膜成膜性能研究主要研究典型的小分子成膜化合物(二十二酸)在纯水和金属离子cd ~ ( 2 + )两种亚相下分子聚集过程,详细讨论了膜的形成和相变过程,分析了纯水和金属离子cd ~ ( 2 + )两种亚相情况对各状态下膜的静态弹性的影响;同时考查dppc单分子膜相变过程,同时研究了在不同压力处、不同压膜速度条件下对分子膜稳定性的影响。 |
| 7. | Considering the advantages of lb films technology in making biosensor and present research status of urease biosensor , in this thesis , we have prepared urease / amphiphile mixed lb films and pure urease lb films , and transferred the films onto the surface of signal transducer by the lb films technology . the characteristics of the urease biosensors are investigated subsequently 鉴于lb膜技术在制作生物传感器方面的优点以及脲酶生物传感器的研究现状,本论文制备并优化了脲酶两亲性化合物混合lb膜和纯脲酶langmuir膜的成膜条件;并采用lb膜技术将其转移到信号转换器表面,研究了其脲酶生物传感器的特性。 |
| 8. | The study of in - situ construction of cytocompatible surface on pdl - la matrix via amphiphile - amino acid ( rgd ) hybrid self - segregation - the amphiphilic diblock copolymer , poly ( dl - lactide ) - poly ( ethylene oxide ) ( pla - peo ) copolymer , containing hydrophobic pla block and hydrophilic peo block was synthesized via coupling method in this dissertation . cell - adhesion - promoting amino acids and integrin receptor peptide rgd were then immobilized at the end of peo chain of pla - peo copolymer via hydroxyl group activation technique . the solvent blending and casting method was then used to obtain the amphiphile modified pdl - la membranes 两亲共聚物-氨基酸( rgd )杂化体原位自修饰构建聚乳酸细胞相容性表面的研究一本论文首先设计并合成了一类含疏水聚乳酸( pla )链段和亲水聚氧乙烯( peo )链段的两亲嵌段共聚物材料( pla - peo ) ,利用peo链端的活性官能团羟基固定了促细胞粘附的氨基酸及整合素配体多肽片段rgd 。 |
| 9. | 2 . urease - based field effect transistor biosensor has been fabricated by the transfer of urease / amphiphile mixed langmuir films onto ion - sensitive field effect transistor ( isfet ) . its function has been studied with isfet meter , and the intensity of output signals shows linear relationship with the logarithmic urea concentration from 0 to 20 mm 用lb膜技术将脲酶两亲性分子混合langmuir膜转移到离子敏感场效应晶体管( isfet )表面,制成了脲酶场效应晶体管生物传感器;采用离子敏感场效应管特性测定仪对它的性能进行了分析。 |