| 1. | In the ovariectomized mice , progesterone had no effects on caveolin - 1 expression
这些结果表明，小窝蛋白在子宫中的表达可能需要胚胎刺激。 |
| 2. | Estrogen down - regulated caveolin - 1 mrna expression in the stroma , while progesterone could increase caveolin - 1 mrna expression in the estrogen - treated mice
在切除卵巢的小鼠子宫中，孕酮对小窝蛋白- 1mrna和蛋白的表达没有影响。 |
| 3. | In conclusion , these results suggest that caveolin - 1 expression may be closely related to embryo implantation and decidualization by regulating vascular permeability and angiogenesis
雌激素可下调小窝蛋白- 1mrna在子宫基质中的表达，而孕酮可恢复雌激素的下调作用。 |
| 4. | In the uterus under delayed implantation , caveolin - 1 expression was detected in the almost stroma cells , while caveolin - 1 expression was mainly shown in the stroma and vascular endothelial cells in the primary decidulization zone after activation
在延迟着床的小鼠子宫中，小窝蛋白- 1mrna和蛋白散在表达于基质细胞和基质中的血管内皮上。 |
| 5. | Under artificial decidualization , caveolin - 1 mrna and immunostaining were mainly seen in the decidualized cells and vascular endothelial cells at the mesometrium side . both caveolin - 1 mrna and immunostaining were observed in the stroma on days 4 and 5 of pseudopregnancy
在假孕小鼠子宫中，小窝蛋白- 1的mrna和蛋白主要定位在第4 5天的基质细胞和基质中血管内皮上。 |
| 6. | The aim of this study was to examine caveolin - 1 expression and regulation in mouse uterus during early pregnancy , pseudopregnancy , delayed implantation , artificial decidualizarjon and hormonal treatment by in situ hybridization and immunohistochemistry
在妊娠第1天的子宫肌层中，可以检测到小窝蛋白- 1mrna和蛋白的表达。在第3 - 4天的子宫基质中可以检测到小窝蛋白- 1mrna和蛋白的表达。 |
| 7. | The expression of caveolin - 1 mkna and immunostaining were strong in myometrum on dey 1 of pregnancy . there were detectable caveolin - 1 mrna and immunostaining in the stroma from days 3 to 5 of pregnancy . a strong level of caveolin - 1 expression was observed in the decidualized cells and vascular endothelial cells at mesometrium side from days 6 to 8 of pregnancy
小窝蛋白- 1在妊娠第5天的基质中以及第6 - 8天的子宫次级蜕膜区有较强的表达，特别是在第6 - 8天系膜侧的次级蜕膜区的蜕膜基质细胞及血管内皮细胞中表达很强。 |
| 8. | Caveolae domains are found in most cell types , particularly in terminally differentiated cells . caveolin - 1 , as the primary structural component ofcaveolae , plays a pivotal role in many signal transduction passways by regulating signaling molecules and participates in many physiologic processes , including apoptosis , angiogenesis , and sperm capacitation
小窝蛋白- 1在多条信号转导通路中发挥着枢纽作用，通过调节这些信号转导通路相关信号分子的活性，参与调节细胞凋亡、血管发生、精子发生以及精子获能等生理过程。 |
| 9. | Lipid rafts and caveolae are found to be essential for insulin - like growth factor ( igf ) - 1 receptor signaling during 3t3 - l1 preadipocyte differentiation induction . in 3t3 - l1 cells , igf - 1 receptor is located in lipid rafts and caveolae of the plasma membrane and can directly interact with caveolin - 1 , the major protein component in caveolae
通过免疫荧光和纯化脂质筏/质膜微囊的方法，发现igf - 1受体定位于脂质筏和质膜微囊中，而且igf - 1受体可以直接和微囊素1相互作用。 |
