| 1. | The expression level of vegf in tumor tissue is correlated with the serum level of vegf . we testified the existing of cecs and ceps in pb
微血管密度（ mvd ）与vegf表达水平及外周血“ c cep无关，而肿瘤局部vegf表达水平与血清vegf水平相关。 |
| 2. | The ceps can differentiate and expand into mature endothelial cells . and cecs / ceps and vegf are helpful in tumor matastasis , prognosis and gene therapy research
同时，血管内皮细胞体外分化扩增方法的建立，为血管内皮细胞功能、以及抗血管基因治疗等的深入研究奠定了基础。 |
| 3. | Ceps can be used by companies when submitting an application for marketing authorisation , and replaces much of the documentation required for the active substance in the marketing authorisation dossier
当公司递交销售许可申请时可以使用cep证书，在销售许可申请档案中替换活性物质所要求的文件。 |
| 4. | Ceps are certificates issued by the edqm ( european directorate for the quality of medicines ) , to confirm that a certain active substance is produced according to the requirements of the relevant monograph of the european pharmacopoeia or of the monograph on tse
Cep证书是由edqm （欧洲药品质量管理局）颁发的，用以证明某个活性物质是根据欧洲药典的相关专论或tse专论的要求来生产的。 |
| 5. | Now it has been found the recruitment and homing of circulating endothelial cells ( cecs ) or their progenitors ( ceps ) released from the bone marrow is very important in tumor angiogenesis . we detected the cecs and ceps in 64 pb ( peripheral blood ) of tumor patients . we found the amount of cecs and ceps is higher in tumor patients than normal controls
本项目应用流式细胞法对64例肿瘤患者及15例正常人，外周血中的循环血管内皮细胞( circulatingendothelialcell ， cec )以及骨髓来源的循环血管内皮前体细胞( circulalingendothelialprecursor ， cep )进行了检测，证实了外周血中cec / cep的存在，发现肿瘤患者cec / cep含量高于正常对照组，提示肿瘤患者体内存在血管内皮及其前体细胞的动员。 |
| 6. | Using of g - csf / gm - csf can mobilize the cec / cep . the amount of cecs / ceps is correlated with the serum level of vegf > vcam - k 1cam - 1 > bfgf , which indicate that these cytokines are related to cec / cep mobilization . the ceps can differentiate into mature endothelial cells in vitro which is testified by electron microscope and immunohistochemistry
经造血干细胞动员( g - csf / gm - csf )后，外周血中cec / cep升高，证实生血因子在动员造血干细胞的同时，对血管内皮干/祖细胞亦有动员作用。 |
