Chinese translation for "hla单倍型"
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- hla haplotype
Related Translations:
hla: 白细胞特异性和组织相关融性拉人白细胞a位点人白细胞抗原人白细扁抗原人体白细胞抗原是人类白细胞抗原系统同种白细胞抗原硬皮甲主要组织相容性复合体组织相容性抗原
- Example Sentences:
| 1. | At present , in an attempt to stimulate specific antitumor immunity , experimental models and clinical studies are currently evaluating the potent antigen - presenting capacity of dc combined with single or multiple tumor antigen epitopes . however , there are several problems in utilizing pulsing dc with synthetic immunodominant peptides from identified antigens . 1 ) the potential induction of tolerance ; 2 ) the need to determine the patient ' s hla haplotype , the limitation of therapy to patients whose tumors express defined specific tumor antigens in the context of the correct hla phenotype , the unavailability of peptides for all hla haplotypes ; 3 ) the lack of cd4 help cell - related epitopes for most antigens ; and 4 ) the ctl resulting from such protocols have a good in vitro capacity to kill peptide - pulsed target cells but only a modest capacity to kill tumor cells
但是，学者们发现这一疗法存在着如下的缺陷：单一ctl表位抗原肽的应用其抗肿瘤作用弱于多种肿瘤抗原的联合应用，且有诱导免疫耐受的潜在危险，有时反而会促进肿瘤的生长；事先需对患者的hla单倍型进行鉴定，以确定ctl表位与hla单倍型是否匹配，目前尚缺乏能与所有hla单倍型相匹配的ctl表位，从而限制了这一疗法的应用；这一疗法所产生的ctl在体外能有效杀伤经肿瘤抗原肽共孵育过的靶细胞，但对肿瘤细胞的杀伤能力较弱：这种l表位抗原肽缺乏cd4汀h细胞相关的表位，因此，不能诱导有效的th细胞免疫应答。 |
- Similar Words：
- "hlawzingon" Chinese translation, "hlay" Chinese translation, "hlaⅠ级抗原" Chinese translation, "hla标志假说" Chinese translation, "hla补体单倍型" Chinese translation, "hla复合体" Chinese translation, "hla抗体" Chinese translation, "hla抗体介导的输血反应" Chinese translation, "hla抗原" Chinese translation, "hla抗原存在" Chinese translation
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