Although there are a number of differences in the pathogenesis and clinical features of diabetic macroangiopathy and microangiopathy , these two entities often coexist and induce mutually worsening effects 尽管在糖尿病大血管病变和微血管病变上的病理和临床特征有许多不同,然而这两类病变常常同时存在并且彼此加剧。