Estrogen ( e2 ) is one of the steroid hormones , which is mainly synthesized and secreted by the gonad affecting proliferation , differentiation and function exerting of target tissues . circumferential estrogens were mainly produced by ovary and spermary , and the brain estrogens came mostly from hypothalamus , neurons of limbic system and neuroglias 雌激素四）是由芳香化酶催化雄激素转化而来的，它影响靶组织的生长分化和功能发挥，外周雌激素主要由卵巢、睾丸产生，脑内主要由下丘脑、边缘系统的神经元和神经胶质细胞产生。
3.
Axoplasmic transport of nerve fibers ; nutrition of nerve fibers ; the function of neuroglia cells ; eletrical synapse ; contact ways of central neurons ; local circuit neurons ; central facilitation ; body sensory afferent pathway , visceral sensation ; the regulation system of somatic motor , the central regulation of visceral sensation ; pain sensation ; the function of basal ganglia ; evoked cortical potential and electroencephalogram 神经纤维的轴浆运输；神经纤维的营养；神经胶质细胞的功能；电突触；中枢神经元的联系方式；局部回路神经元；中枢易化；身体感觉传入通路，内脏感觉；躯体运动的调节系统，内脏活动的中枢调节；痛觉；基底神经节的功能；皮层诱发电位和脑电图。
4.
There are distributed in different regions and with different densities in the brain , so it can be supposed that il - 2 has physiological functions in these different regions . for instance , il - 2 has the nutrition function on the neurons and neuroglias , and affects the release of neurotransmitter . it has been tested that il - 2r can be expressed in oligodentrocytes and microglias Il - 2r在中枢神经系统中有广泛表达，且不同脑区il - 2r的分布及密度不同，推测il - 2因而发挥不同的生理功能，如其能影响营养神经元和神经胶质的功能，影响神经递质的分泌等。
