Therefore , this project intend to explore mechanism of apoptosis mediated by protein tyrosine kinase ( ptk ) pathway by study of the role of erk1 / 2 , jnk and p38 in apoptosis of u 2 - os cell line induced by bfgf 本课题欲通过研究erk1 2 、 jnk 、 p38在bfgf诱导u2 - os细胞凋亡中的作用来探讨酪氨酸蛋白激酶途径参与细胞凋亡调控的作用机制。
