The repressor is essentially a negative control mechanism . 阻遏物基本上是一种负控制机制。
2.
Effect of extracellular - signal regulated kinase 1 2 specific repressor pd98059 on murine lymphocyte proliferation 98059对小鼠淋巴细胞增殖的影响
3.
The regulator may code for a repressor protein that switches off an operator gene ( in bacteria ) 调解基因可能编码一种抑制蛋白,能够关闭一个操纵基因(在细菌中) 。
4.
To search proteins that associate with the mouse mint protein and regulate notch signaling in nuclei , and to study the function and mechanism of mint - mediated transcription repression , yeast two - hybrid assay was used to screen proteins that interact with a fragment of mint ( f5 , amino acids 2226 - 2959 ) . from 4x106 yeast clones transformed with the bait plasmid and a cdna library of 9 dpc mouse embryo , fifty - one were positive for nutritional screening and p - galactosidase assay . restriction digestion identified 10 independent positive clones and these were analyzed by dna sequencing these clones represent 3 correctly fused cdna fragments , which are mint , alpha a - crystallin - binding protein i ( alphaa - crybpl ) , and nuclear receptor co - repressor 1 ( n - corl ) , respectively 鉴于mwt基因编码区较长,共有10799个碱基,故此我们将mint分为六段,分别命名为fi一f6 ,本研究以其中的f5 ( 222e959 )和f6 ( 296s576 )片段为研究对象,将h者分别插入pgb盯7载体中,结果显示: mintfs可与核受体辅助抑制因子1阶cori ) , o晶状体蛋白结合蛋白1hlphatcrybp入及mw加互作用,而f6可与igm的重链恒定区、泛素结合酶2l6和一个未知功能的新的蛋白基因进行结合。
5.
Aes contains a glutamine - rich ( q ) domain in its n - terminal , which sharing high homology with the amino terminal region of groucho / tle ( transducin like enhancer of split ) . the function of aes is not clear yet , while groucho / tle were found to be a family of transcription co - repressor and play impo rtant roles in notch signaling , wnt - 0 catenin signaling and other transcription regulation events Aes的n -末端约130个氨基酸中富含谷氨酰眩( q )残基,形成一个q结构域,与转录协同抑制分子tle ( transducinlikeenhancerofsplit )的氨基端高度同源。