| 1. | Results : a fragment of 896bp was got by rt - pcr , which contains the coding sequence of sh2 a gene
结果rt pcr扩增得到sh基因编码序列， genbank登录号为ay190323 ；连接到pcdna3 |
| 2. | The effect of sh2a gene in cell signal transduction : sh2a is a novel member of sh2 signaling protein family
讨论一3h基因对细胞信号转导的影响sh基因是sh 。信号蛋白家族成员之一。 |
| 3. | They play an important role in signal transductions by tyrosine protein kinase . sh2 domain is considered as " protein recognize
结构域视为”蛋白质识别密码” ，表示它控制和预测蛋白质一蛋白质的相互作用。 |
| 4. | So , we analysed its characterization . it consists of 2 . 8kb cdna with 1362bp orf and codes 454 amino acids with only a sh2 domain
8kb ，由9个外显子和8个内含子组成，编码的蛋白质有454个氨基酸，含有一个sh 。 |
| 5. | Sh2 domain can specifically recognize phosphated tyrosine residue , and mediate receptor tyrosine protein kinase signal transduction
Shz结构域可以特异性识别磷酸化酪氨酸短序列，介导受体酪氨酸蛋白激酶信号转? 2 ?导途径。 |
| 6. | Sh2 a is a novel docking protein of sh2 signaling protein family , which plays an important role in cellular signal transduction pathway
信号蛋白家族的新成员，在酪氨酸蛋白激酶相关受体介导的信号传导中起一种接头蛋白的作用。 |
| 7. | Sh2a is a novel docking protein of sh2 signaling protein family , which plays an important role in cellular signal transduction pathway
09 。 sh是sh 。信号蛋白家族的新成员，在酪氨酸蛋白激酶相关受体介导的信号传导中起一种接头蛋白的作用。 |
| 8. | Sh2 family plays an important role in signal transduction by tyrosine protein kinase . the expressional difference between tumor and tumor neighboring tissue suggested sh2a may relate to tumor onset or development
在多种肿瘤癌组织及癌旁组织中表达差异提示，它与肿瘤发生发展有一定的相关性。 |
| 9. | In the previous work , we cloned sh2a gene in this region by exon trapping and exon linking , which is a novel member of sh2 family . sh2 domain is considered as " protein recognized code "
在前期工作中，运用外显子捕获和外显子拼接等策略，我们在这一区域克隆了sh _ 2a基因，是sh _ 2信号蛋白家族的新成员。 |
| 10. | 8kb cdna with 1362bp orf and codes 454 amino acids with only a sh2 domain . the gene was named as sh2a at chromosome 8p22 . we study its structure by blast homologous analysis and its expression by rt - pcr and northern blot
本文将通过蛋白质分析软件研究其结构和同源性，利用rt - pcr和northern印迹杂交技术研究该基因的表达情况及该基因与肿瘤的关系。 |
