8kb cdna with 1362bp orf and codes 454 amino acids with only a sh2 domain . the gene was named as sh2a at chromosome 8p22 . we study its structure by blast homologous analysis and its expression by rt - pcr and northern blot 本文将通过蛋白质分析软件研究其结构和同源性,利用rt - pcr和northern印迹杂交技术研究该基因的表达情况及该基因与肿瘤的关系。