Introduction positional cloning of disease genes and research of protome become very important in the post - genome period after completion of human genome project ( hgp ) . positional cloning is a new mean with the developing of hgp 前言人类基因组计划的测序工作完成之后，已进入后基因组学阶段，疾病基因的定位克隆及其蛋白质功能研究已成为研究的重要内容。
