Methods the solid dispersion of estradiol was prepared using pvp k30 as a carrier by the solvent method ; dissolution and dialysis were used to compare the release rate between estradiol capsules and estradiol tablets respectively 方法以聚维酮k30为载体,溶剂法制备雌二醇固体分散微粒;采用溶出度测定仪和动态透析2种方法分别评价优化后的处方及对照片剂的体外药物释放情况。