| 1. | Dendritic cells induced anti - tumor immunotherapy
树突状细胞介导的肿瘤免疫治疗 |
| 2. | Cell - mediated immunity
细胞介导的免疫 |
| 3. | The immunoinflammatory reaction induced by glia is one of the major pathogenetic factors
胶质细胞介导的免疫炎症反应是导致该疾病发生的主要因素之一。 |
| 4. | Immunoregulation mediated by regulatory t cell is one of the most important mechanisms to maintain self tolerance
调节性t细胞介导的免疫调节是自身耐受的重要机制之一。 |
| 5. | Aim : il - 12 is an imunoregulatory cytokine that plays an essential role in cell - mediated immunity
目的： il - 12是一种具有免疫调节功能的细胞因子，在细胞介导的免疫反应中起着关键作用。 |
| 6. | D . nodosus pili is the main protective immunogen against footrot in ruminants . il - 2 is known to be as an adjuvant in many areas
已有很多实验证明il - 2作为佐剂能提高体液免疫和细胞介导的免疫反应。 |
| 7. | The bone - resorption mediated by osteoclasts was analyzed to exemplify the sequence of biological events and the chemical problems unsolved
以破骨细胞介导的骨再吸收过程为例阐述过程中的生物事件顺序，提出有待解决的化学问题。 |
| 8. | Dendritic cells ( dc ) is the most powerful apc , which can markedly increase the antigen - presentation capacity by maximizing the pepitide - mhc complexes on the cell surface and upregulating the co - stimulatory ligands b7 - 1 and b7 - 2 , adhesion moleculees such as il - 12 that promote full activation of lymphocytes . full activation of antigen - specific t cells requires two signals - one signal coming via the tcr and the other signal through engagment of co - stimulatary molecules . t cells receiving one signal via their tcr are turned off by mhc ( major histocompatibility complex ) , via t cell cd28 binding to b7 on the dc induce tlymphokine and t cell proliferatiion
T细胞介导的细胞免疫在控制肿瘤生长方面发挥着重要作用， t细胞在发挥抗瘤效应(分泌细胞因子和直接杀伤)之前必须先经过活化，体内专职抗原提呈细胞( apc )细胞并使其活化，树突状细胞( dendriticcell , dc )为t细胞的激活提供双重信号， t细胞借助tcr识别由dcmhc分子递交的抗原肽后，通过tcr - cd3复合体传递抗原特异性识别信号(第一信号) ，以cd28为主的t细胞表面辅佐分子识别dc表面b7分子，传递非特异性协同刺激信号(第二信号) ，在机体抗肿瘤免疫应答中处于核心地位。 |
| 9. | Since their original identification by steinman , much attention is being focused on the role of dc in eliciting antitumor immunity and in the potential therapeutic applications . in recent years , it was found that several cytokines support the in vitro differentiation and maturation of dc derived from bone marrow or blood progenitor cells
近年来，随着dc大量培养技术的建立和成熟， dc的功能得到了较深入的研究，在人和动物模型中已经证实，由t细胞介导的抗原特异性免疫应答在机体抗肿瘤中起着主导作用。 |
