| 1. | Main task : study the immune - related signaling pathway
主要研究任务：免疫细胞信号传导通路分子机制的研究。 |
| 2. | " for their discovery of g - proteins and the role of these proteins in signal transduction in cells
发现g -蛋白及其在细胞信号传导中的作用 |
| 3. | The cell signal transduction of cervical intervertebral disc of rat and the regulating effects of yiqihuayu fang
椎间盘细胞信号传导及益气化瘀方调控机理的研究 |
| 4. | Awry cell signaling is commonly found in pathologies such as cancer , cardiovascular disease , and diabetes
细胞信号传导途径出错在癌症、心血管疾病、糖尿病和大多数疾病中常常出现。 |
| 5. | The process of transmitting and transduction of signals participates in and affects almost every aspect of life processes and is vital to cell survival and functions
细胞信号传导涉及生命过程的各个方面，关乎细胞机体功能及生存。 |
| 6. | When bound to calcium ions , calmodulin changes shape and phosphatases , that are involved in signaling pathways , activating or inactivating them
钙调蛋白本身没有活性，当和钙离子结合后，会引起钙调蛋白构象的改变，使之与其他蛋白酶如激酶或磷酸酶结合，调节细胞信号传导。 |
| 7. | Disruption of signaling pathways impairs body functions leading to diseases and death . the understanding of cell signaling mechanisms and pathways is , therefore , crucial to innovative drug development and our combat against diseases
因此，信号传导紊乱将导致人体功能障碍、疾病、甚至死亡，对细胞信号传导机制及通路的了解已成?药物创新、防治疾病的关键。 |
| 8. | To some extent , chinese materia medica are multi - locus directional gene regulators , and it is difficult to get to complete understanding of the pharmacological mechanism of chinese medicine on the gene level in decades of years , for the complicated ingredients and various kinds of chinese material medica , while the methods based on gene network and cell signal transducting system ore routine methods already in research of western medicine
从其中的一个角度来看，中药是一种多位点定向或定点改变基因表达的技术；但是中药成分复杂，系统庞大，很难在几十年的时间内实现在基因水平上对中药的全面理解；而西药已经把基于基因网络和细胞信号传导系统结构的药物设计方法变成了常规技术。 |
| 9. | For example , as a direct toxic effect , periodontal iruses and bacteria and their products ( endotoxins or enzymes , for example ) are toxic to surrounding cells and may directly induce mutations in tumor suppressor genes and proto - oncogenes or alter signaling pathways that affect cell proliferation or surial of epithelial cells
例如，作为直接毒性作用，牙周病毒和细菌及在细胞周围其产生的毒性物质（例如，类毒素或酶类）可直接诱导肿瘤抑制基因和原癌基因突变或者改变细胞信号传导通路从而影响上皮细胞增殖或存活。 |
| 10. | For example , as a direct toxic effect , periodontal viruses and bacteria and their products ( endotoxins or enzymes , for example ) are toxic to surrounding cells and may directly induce mutations in tumor suppressor genes and proto - oncogenes or alter signaling pathways that affect cell proliferation or survival of epithelial cells
例如，作为直接毒性作用，牙周病毒和细菌及在细胞周围其产生的毒性物质（例如，类毒素或酶类）可直接诱导肿瘤抑制基因和原癌基因突变或者改变细胞信号传导通路从而影响上皮细胞增殖或存活。 |
