| 1. | Patch clamp technique and its application in cardiovascular pharmacology
膜片钳技术及其在心血管药理学中的应用 |
| 2. | Blind patch clamp whole - cell recording technique for neurons in hippocampal slices
海马脑片盲法膜片钳全细胞记录技术 |
| 3. | Abstract : the study of lens cells by patch clamp technique began in th e early 90 " s
文摘:应用膜片钳技术对晶体细胞的研究始于90年代初。 |
| 4. | Rapid dissociation of hippocampal neurons from neonate rats by the whole - cell patch - clamp technique
新生大鼠海马神经元的急性分离与膜片钳技术 |
| 5. | These channels are responsible for the modulation of the hydr ation state and transparency of lens
在晶体电生理特性研究中，多种模式的膜片钳技术得到了广泛应用。 |
| 6. | In the present study , using the conventional whole - cell mode and perforated whole - cell patch claxnp mode , the role of intracellular and extrce1lular calcium in snp - induced increase of ik ( . . ) were investigated . l
我们分别应用传统全细胞模式和穿孔模式的膜片钳技术，研究了细胞内外钙离于在s p诱导人h ）增加中的作用，进而阐明no引起豚鼠胃窦环行肌舒张的离子机制。 |
| 7. | Professor jun chen has published about 50 scientific papers in international or domestic scientific journals with more than 20 international journal papers cited by sci of us institute of scientific information . he also edited a book entitled as experimental techniques of patch clamp and two chapters of other books
50余篇，其中被sci收录的国际期刊论文20余篇（均为责任通讯作者） ，主编著作《膜片钳实验技术》 1部，参编专著2部。 |
| 8. | Activities of bkca channels were studied at the single - channel level with inside - out patch - clamp configuration . . bkca channels in neurons after reoxygenation for 6 h showed a significant increase in the unitary conductance and open probability compared with control . after reoxygenation for 24 h , both the conductance and the open probability recovered to the control level
采用膜片钳内面向外式单通道记录方法研究发现，复氧6小时神经元bkc ：通道电导及开放概率与正常对照组相比均显著增加，复氧24小时通道电导及开放概率恢复至正常水平。 |
| 9. | Here , aba - induced h2o2 generation and their roles in inducing stomatal closing were investigated by epidermal strips bioassay , laser scanning confocal microscopy and patch clamp with ios5 and its wild type plant as materials . there were no clear differences between wild type and ios5 in the density , shapes and aperture of their stomata
本文以los5及其相应野生型为材料，采用表皮条生物分析、激光扫描共聚焦显微技术及膜片钳技术研究了nacl胁迫条件下， aba诱导保卫细胞内h _ 2o _ 2的产生及二者在诱导气孔关闭中的作用。 |
| 10. | The patch clamp experiment : the cell - attached and inside - out configurations of the patch - clamp techniques were used to investigate single channel properties of nmd a receptors in the actuely dissociated neurons of the marginal division in the rat striatum , recording the current amplitude . long / short term opening / closing times indexes and the effects of incitants and agonists of the nmd a receptors on those parameters . we find that two types of conductance of 42ps and 20ps were recorded , the 42ps was the advantaged conductance
本研究是在本实验室以前研究的基础上，通过膜片钳( pachclamp )观测sd ( sprague - dawley , sd )的mrd上nmda受体通道的电生理特性；继而对青壮年sd大鼠的mrd 、海马进行毁损并腹腔注射nmda受体阻滞剂ktm ( ketamine , ktm ) ，观察其对大鼠学习记忆能力的影响：对于学习记忆能力下降的老年鼠进一步做颅内定位注射nmda受体激动剂与抑制剂，观察其在特定部位的作用；最后，应用fmri ( functionalmagneticresonanceimaging ; fmri )对注射ktm的志愿者做学习记忆与痛觉的对比观察。 |
