| 1. | Application of organic mass spectrometry to drug metabolism research
有机质谱在药物代谢研究中的应用 |
| 2. | The dosage regimen required to attain and maintain the appropriate concentration depends on pharmacokinetics
达到和维持适当药物浓度所需要的给药方案应该根据药物代谢动力学制定。 |
| 3. | Linked pharmacokinetic and mechanistic studies within these trials will allow for optimizing drug dosing and monitoring
这些试验中的相关的药物代谢动力学和机械学的研究将会考虑到优化药物定量和监测。 |
| 4. | From the point of pharmacokinetic , this paper reviews the present state of the absorpation , distribution and invertion of nano - drugs
该文从药物代谢动力学的角度综述了纳米药物的吸收、分布和转化的研究进展。 |
| 5. | However , trials of il1ra for osteoarthritis have had limited success , primarily because the drug tends to break down quickly , according to the researchers
然而il - 1受体拮抗剂治疗骨关节炎的临床实验仅取得有限成功，研究人员认为主要是因为药物代谢太快。 |
| 6. | Chunna yu , linya you , su zeng . studies on the recombinant drug metabolizing enzymes . the eighth national conference on drug and xenobiotics metabolism in china , dalian , october 2006
俞春娜，尤琳雅，曾苏，重组药物代谢酶的研究与应用，第八次全国药物与化学异物代谢学术会议，大连， 2006年10月。 |
| 7. | Generally , we recommend that metabolites identified in human plasma that account for greater than 10 percent of drug related material ( administered dose or systemic exposure whicheer is less ) be considered for safety assessment
我们推荐:一般来说,如果人血浆中检测到的药物代谢产物浓度超过药物相关物质的10 % (无论是药物给予量还是全身接触因素) ,就需要考虑安全性评估 |
| 8. | Glucuronidation catalyzed by ugts have been a subject of intense research during the last decades , but no domestic literature was found about the investigation in this area , and the establishment of ugts transgenic cell lines is not reported either
在建立葡醛酸缀合酶转基因细胞系方面国内还未有报道，药物的葡醛酸缀合反应研究在国际上也是近十年才达步开展起来的一个药物代谢研究领域 |
| 9. | " results of the pharmacokinetic analysis - which revealed that higher plasma concentrations were associated with greater response rates - further reinforce the recommendation that , whenever possible , posaconazole should be taken with food or a nutritional supplement to maximize exposure , " the investigators add
“药物代谢动力学分析结果表明，药物血浆浓度同疗效呈正相关，如果可能的话，应该强烈推荐泊沙康唑作为食品或营养补充使其疗效最大化， ”研究人员补充道。 |
| 10. | Morphine injection from extradural cavity 、 subarachnoid cavity 、 ventricle of cerebrum can have an obvious effect in treating intractable pain resulting from cancer by binding its receptor in spinal cord and centra with reduced dosage and side effect . this article reviews this drug about its usage , quantitative titration formula in theory and pharmacokinetic character
硬膜外腔、蛛网膜下腔、脑室内注射吗啡可以集中其脊髓吗啡受体及中枢吗啡受体作用而对顽固性癌痛有效,并且因用量减少而副作用减少,本文介绍其用法及量的滴定理论公式以及药物代谢动力学特点。 |
