| 1. | Joan: i am going to put a most solemn question to you .
琼，听我问你一个极为重大的问题。 |
| 2. | If i had any major problems with him, i just blocked them out .
如果我同他之间存在什么重大的问题，我就把这些问题冻结起来。 |
| 3. | With something so important, you can't just wave a wand and presto !
在这么重大的问题上，你想挥动一下指挥棒，转眼就变过来，办不到！ |
| 4. | I was present at both these cabinets, and was not aware that any significant issue was still pending .
这两次内阁会议，我都参加了，并没有感到尚有任何重大的问题悬而未决。 |
| 5. | After the fall of paris, when hitler danced his jig of joy, he naturally dealt with very large propositions .
巴黎陷落以后，希特勒欣喜若狂，这时，他自然要应付极端重大的问题。 |
| 6. | We have encountered major problems
我们已遇到重大的问题。 |
| 7. | The use of stem cells in research asks a number of important questions
干细胞在科研中的使用引发了许多意义重大的问题。 |
| 8. | The problems with database size boil down to a more fundamental problem , however
然而，数据库大小的问题还会引起更重大的问题。 |
| 9. | Construction noise in a compact city like hong kong can be a significant problem
香港人烟稠密，建筑噪音无疑是一个重大的问题。 |
| 10. | In the long run , the bigger question is whether the two approaches can somehow be made compatible
最终，更重大的问题是这两条道路能否通过某种方式协调一致。 |
