| 1. | Mutation screening of epithelial sodium channel gene in a
综合征家系上皮钠通道基因突变的研究 |
| 2. | A study of mutation of the epithelial sodium channel gene in a
综合征家系临床和上皮细胞钠通道基因突变的研究 |
| 3. | Sodium channel plays a major role in the resistance to synthetic pyrethroids in insects
钠通道在昆虫拟除虫菊酯抗药性中的重要作用 |
| 4. | Effect of atx on opening modes of myocyte sodium channel , action potential and qt intervals of ecg
海葵毒素对心肌钠通道开放模式动作电位及心电图 |
| 5. | Effects of droperidol on persistent sodium channel currents of pyramidal cell in hippocampal ca1 area of rats with cerebral ischemia
1区锥体细胞持续钠通道电流的影响 |
| 6. | These anaesthetics block sodium channels and thereby the excitability of all neurons , not just sensory neurons
这些局麻剂可以阻断钠通道，因此不仅仅阻滞了感觉神经元，也同时阻滞了几乎所有其他神经元的兴奋性。 |
| 7. | These included mutations in the sodium channel gene scn5a , preiously associated with lqts and other unstable heart rhythm conditions and sudden death
这其中包括钠通道基因scn5a的突变，该基因以前发现与lqts 、其他不稳定心律失常以及猝死相关。 |
| 8. | Most local anaesthetics used clinically are relatively hydrophobic molecules that gain access to their blocking site on the sodium channel by diffusing into or through the cell membrane
大多数应用于临床的局麻药物都是相对疏水性的分子，可弥散通过细胞膜，作用于阻滞部位的钠通道。 |
| 9. | Unfortunately , the pharmaceutical industry has so far been unable to successfully develop selective inhibitors for such channels , in part because they closely resemble ttx - sensitive sodium channels , which appear widely throughout the nervous system
不幸的是，至今制药界仍未成功研发出这种通道的选择性抑制剂；部份原因是它与广泛分布于神经系统的ttx敏感型钠通道十分近似。 |
| 10. | So the results indicate that the two mutants have no significant difference in the toxicity of inhibiting mammal neuron sodium channels , and ala20 or ser20 was not the key residue . the two peptide neurontoxins inhibite mammalian voltage - gated sodium channels through a novel mechanism distinct from other known spider toxins such as 5 - actxs , - agatoxins i - vi which banded receptor site 3 to slow the inactive time course of sodium channels . we suggest that hntx - v maybe target the site 1 of sodium channels in a similar manner to - conotoxins and ttx
同时两种海南捕鸟蛛毒素从影响ttx一s钠通道的方式上来看，与其它已知肤类蜘蛛毒素如6一actxs等通过作用于位点3引起延缓钠通道的失活时间存在明显不同，我们推测hntx一iv和iintx一v可能是以一种新的不同于其它蜘蛛毒素的方式来影响钠通道的，而ttx一s钠通道位点1则很有可能便是它们的作用位点，与ttx和林一eonotoxins相似。 |
