The synthesis and sterochemistry of 1 , 5 - benzothiazepines - - amino - - lactam derivatives 内酰胺的合成和立体结构研究
2.
Mrsa is a type of staphylococcus aureus that is resistant to beta - lactam antibiotics 抗药性金黄葡萄球菌是金黄葡萄球菌的其中一种，对beta - lactam类药物呈抗药性。
3.
Mrsa is a type of staphylococcus aureus that is resistant to beta - lactam antibiotics 抗药性金黄葡萄球菌是金黄葡萄球菌的其中一种，对? - lactam类药物呈抗药性。
4.
Resistant strains are less likely to develop if a single dose or brief course of a ? lactam antibiotic is administered 大多数常见的病原体为肠道细菌，如大肠杆菌和变形杆菌和假单胞菌。
5.
The principle , characteristics and recent applications of - lactam antibiotics are introduced and reviewed . moreover , the application prospects and potentiall for both strategies are evaluated 摘要介绍了在-内酰胺类抗生素酶法合成中两大策略的原理、各自特点、目前的应用情况，并将其进行了比较，评价了各自的应用前景及开发潜力。
6.
Panipenem and imipenem exhibited comparable in vitro antimicrobial activity , and their activity against gram - negative bacteria such as k . pneumoniae and enterobacter spp was slightly inferior to meropenem , superior to that of ceftazidime , fluroquinolones and - lactam and - lactamase inhibitor combinations 三种碳青霉烯类抗生素体外抗菌作用优于头孢他啶、 -内酰胺类抗生素与-内酰胺酶抑制剂合剂、氟喹诺酮类等其它受试药物。
7.
D - amino acids as unnatural chiral products are important intermediates in the synthesis of products , such as - lactam semisynthetic antibiotics , antiviral agents , artificial sweeteners , pesticide , peptide hormones , and pyrethroids , etc . though bioconversion of d - amino acids using microbial cells has been realized in industrialization for decades , some limited factors hinder the development of d - amino acid production , and ultimately result in shortage of the raw material in the related industrial fields 目前，用微生物菌体转化生产d -型氨基酸的工艺路线已经产业化，但天然菌体转化工艺存在一些限制因素，阻碍了d -型氨基酸的扩大生产，导致产品短缺。因此，利用基因工程菌生物转化d -型氨基酸已成为世界氨基酸产业的新潮流。
8.
Considering alcaligenes faecalis pencillin g acylase ( afpga ) , which possesses the attractive characteristics for beta - lactam antibiotics conversions , the gene of pga was cloned into two expressing vector pkkfpga and psmlfpga . both the constructed plasmids psmlfpga and pkkfpga contained the pga gene , trc promoter and rrnb transcript terminator , differ in the replicon and antibotic marker , pkkfpga contained multicopy replicon ( cole 1 ) and ampicillin marker . while psmlfpga contained medium - copy replicon ( p15a ) and tetracycline marker 本文将粪产碱杆菌青霉素g酰化酶( afpga )基因构建表达载体pkkfpga和psmlfpga ， pkkfpga和psmlfpga均含trc启动子、青霉素g酰化酶基因、 rrnb转录终止子，其中pkkfpga含有氨卞青霉素抗性基因和cole1高拷贝复制子；而psmlfpga含有四环素抗性基因和p15a中拷贝复制子。
